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Biology · Pharmacology

Medicine Lab

Follow a pill through the body, watch a drug level rise and fall with every dose, and see how receptors, trials and the therapeutic window decide what works.

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The course

7 worlds · 29 lessons

World 1 · The Journey of a Pill

FREEAbsorption, distribution, metabolism and excretion
  1. 01Many doors into the bodyRoutes of administration · 12 min
  2. 02Crossing the gut wallAbsorption · 12 min
  3. 03Spreading outDistribution · 13 min
  4. 04The liver's first passMetabolism · 13 min
  5. 05Leaving the bodyExcretion · 12 min

World 2 · Half-Life and Dosing

PROHow drug levels rise and fall
  1. 01Halving again and againHalf-life · 12 minPRO
  2. 02Doses on repeatBuilding up to a steady state · 14 minPRO
  3. 03A missed doseWhat the curve says · 12 minPRO
  4. 04Loading doses and slow releaseShaping the curve · 13 minPRO

World 3 · The Therapeutic Window

PROEnough to work, not enough to harm
  1. 01Too little, too muchMEC and MTC · 12 minPRO
  2. 02Dose-responseHow effect grows with concentration · 14 minPRO
  3. 03How wide is the margin?The therapeutic index · 12 minPRO
  4. 04Why one dose does not fit everyoneDifferences between people · 14 minPRO

World 4 · Lock and Key: Receptors

PROHow a molecule starts or stops a response
  1. 01Molecules that fitReceptors and binding · 13 minPRO
  2. 02Tight grip, wrong targetAffinity and selectivity · 12 minPRO
  3. 03Switching the response on, off, halfAgonists and antagonists · 15 minPRO
  4. 04Enzymes, channels and pumpsOther targets · 12 minPRO

World 5 · Why Antibiotics Don't Kill Viruses

PROTargets, selectivity and resistance
  1. 01Different kinds of germsBacteria, viruses and fungi · 12 minPRO
  2. 02Hitting the germ, not youSelective toxicity · 13 minPRO
  3. 03Resistance and the full courseWhy prescribers say "follow the course" · 14 minPRO
  4. 04Antivirals and vaccinesA different strategy · 13 minPRO

World 6 · How a New Drug Is Tested

PROFrom idea to approval, and what happens after
  1. 01From idea to candidateTargets, screens and chemistry · 12 minPRO
  2. 02Before humansPreclinical work and Phase I · 13 minPRO
  3. 03Does it really work?Phases II and III, randomisation and blinding · 16 minPRO
  4. 04After approvalSafety monitoring, history and ethics · 17 minPRO

World 7 · Medicines in Daily Life

PROLabels, interactions, evidence and asking for help
  1. 01Reading a labelWhat the leaflet really says · 13 minPRO
  2. 02Mixing and storingInteractions and storage · 13 minPRO
  3. 03Spotting hypeClaims, supplements and evidence · 14 minPRO
  4. 04When to ask a pharmacistSafe-use habits · 14 minPRO
Medicine Lab — interactive 3D lab · Novareka